It's been quite a wee while since I did this sort of stuff, but I hope this helps. Publication no. WO/2005/007178 is what you need for a Google search. I have included a small description of the invention and a few claimx. There is a lot more to read
Pub. No.:
WO/2005/007178
International Application No.:
PCT/NZ2004/000153
Publication Date:
27.01.2005
International Filing Date:
19.07.2004
IPC:
A61K 33/20 (2006.01), A61K 35/74 (2006.01)
Applicants:
BLIS TECHNOLOGIES LIMITED [NZ/NZ]; Level 10 Otago House, Dunedin (NZ) (All Except US).
TAGG, John, Robert [AU/NZ]; (NZ) (US Only).
CHILCOTT, Christopher, Norman [NZ/NZ]; (NZ) (US Only).
BURTON, Jeremy, Paul [AU/NZ]; (NZ) (US Only).
Inventors:
TAGG, John, Robert; (NZ).
CHILCOTT, Christopher, Norman; (NZ).
BURTON, Jeremy, Paul; (NZ).
TREATMENT OF MALODOUR
FIELD OF THE INVENTION This invention relates to methods of inhibiting growth of anaerobic bacteria, particularly halitosis causing bacteria, and to the use of BLIS-producing Streptococcus salivarius strains, extracts thereof, and compositions containing same in the prevention or treatment of halitosis.
CLAIMS: 1. A method for at least inhibiting the growth of anaerobic bacteria sensitive to BLIS-producing S. salivarius, the method comprising contacting the sensitive bacteria with an inhibitory effective amount of a BLIS-producing S. salivarius, or an extract thereof, or a composition comprising said S. salivarius or extract thereof.
2. A method according to claim 1 wherein the anaerobic bacteria are in the oral cavity of an individual.
3. A method of prophylactic or therapeutic treatment of halitosis in an individual in need thereof, the method comprising administering to said individual a BLIS- producing S. salivarius, extract thereof, or composition comprising said S. salivarius or extract thereof, effective to at least inhibit growth of anaerobic bacteria, or in an amount to allow effective colonisation in the oral cavity of the individual by BLIS-producing S. salivarius.
4. A method of controlling the incidence and/or severity of halitosis, the method comprising introducing into the oral cavity of an individual susceptible to halitosis, an amount of a BLIS-producing S. salivarius, extract thereof, or composition comprising said S. salivarius or extract thereof, effective to control the incidence and/or severity of said halitosis.